Asparaginase (E. coli) Solution for injection

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Asparaginase (E. coli) Solution for injection

What is this medicine?

L-ASPARAGINASE (L- a SPARE a gi nase) is used to treat acute lymphocytic leukemia (ALL). It is used in combination with other chemotherapy agents.

How should I use this medicine?

This drug is for infusion or slow injection into a vein. It is sometimes injected into a muscle. It will be given in a hospital or clinic by a trained health care professional.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • feeling faint or lightheaded

  • confusion, agitation, or hallucinations

  • fever or chills, cough or sore throat

  • increased thirst

  • increased amount of urine passed

  • severe abdominal pain

  • severe and sudden headache

  • seizures (convulsions)

  • severe nausea or vomiting

  • shortness of breath, chest pain, or swelling in a leg

  • swelling of any other parts of the body

  • tremors

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • loss of appetite

  • nausea

  • sweating

  • weight loss

What may interact with this medicine?

  • vaccines

  • warfarin

Talk to your doctor or health care professional before taking any of these medicines:

  • aspirin

  • acetaminophen

  • ibuprofen

  • ketoprofen

  • naproxen

What if I miss a dose?

This does not apply. Contact your doctor or clinic if you cannot keep your appointment. It is very important to receive all your treatment as directed to achieve the best results.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorder

  • diabetes or other problems with blood sugar

  • gout

  • history of pancreatitis

  • liver disease

  • take medicines that treat or prevent blood clots

  • an unusual or allergic reaction to L-asparaginase, e-coli proteins, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat. Do not treat yourself.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 7/19/2013
© 2000-2014 The StayWell Company, LLC. 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

We can't find this page

We're sorry, there doesn't seem to be anything at this address.



Please Search for what you're looking for in the top right corner of this page, or visit the homepage

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Request an Appointment 

Find a Doctor

Conditions and Procedures 

Career Opportunities

Billing Information

Directions to Boston Children's Hospital

Boston Children's Hospital Locations

More Patient Resources



Still can't find what you need? Contact Us.

Request an Appointment

If this is a medical emergency, please dial 9-1-1. This form should not be used in an emergency.

Patient Information
Date of Birth:
Contact Information
Appointment Details
Send RequestIf you do not see the specialty you are looking for, please call us at: 617-355-6000.International visitors should call International Health Services at +1-617-355-5209.
Please complete all required fields

This department is currently not accepting appointment requests online. Please call us at: 617-355-6000. International +1-617-355-6000.

This department is currently not accepting appointment requests online. Please call us at: 617-355-6000. International +1-617-355-6000.

Thank you.

Your request has been successfully submitted

You will be contacted within 1 business day.

If you have questions or would like more information, please call:

617-355-6000+1-617-355-6000
close
Find a Doctor
Search by Clinician's Last Name or Specialty:
Select by Location:
Search by First Letter of Clinician's Last Name: *ABCDEFGHIJKLMNOPQRSTUVWXYZ
More optionsSearch
Condition & Treatments
Search for a Condition or Treatment:
Show Items Starting With: *ABCDEFGHIJKLMNOPQRSTUVWXYZ
View allSearch
Visitor Information
“
The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO
Close