Research

Clinical Research

For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2018, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

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Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.

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Resources for the research community

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.

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Would your child benefit from a clinical trial?

Clinical research takes scientific discoveries and transforms them into new treatments and approaches to medical care that improve the health. Learn about the importance of clinical research, its benefits and considerations.

 

Recent Breakthroughs

Erica Esrick, MD, examining Manny, a patient treated with a gene therapy for sickle cell disease

Reviving fetal hemoglobin in sickle cell disease: First patient is symptom-free

Manny Johnson, 21, previously required monthly blood transfusions to keep his severe sickle cell disease under control. After receiving a new gene therapy treatment, he’s been symptom-free for six months.

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shunt tubes

Do antibiotic-impregnated shunts reduce infection in hydrocephalus?

The study, published in the Journal of Neurosurgery Pediatrics, is one of the first randomized prospective trials to directly compare antibiotic and non-antibiotic shunts in children.

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Newborn in nursery at hospital

Gene panel helps investigate sudden unexpected death in children

The Robert’s Program at Boston Children’s is adding a genetic approach to the search for answers for children with sudden unexplained deaths in pediatrics (SUDP).

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Building on our extraordinary leadership in pediatric science at Boston Children’s, we translate our findings — and those of others — to fundamentally change how disease is treated and cured.

David A. Williams, MD
Senior Vice President and Chief Scientific Officer