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Choe Laboratory Research | Overview

The Choe laboratory studies the entry mechanisms of enveloped viruses. In doing so, we have identified the receptors, coreceptors, and the cellular factors involved in the entry steps of various viruses. We also apply our experience in virus entry to translational research; our lab seeks to identify virus entry inhibitors, improve virus vaccines, and develop viral gene therapy vectors that target specific cell types. 


illustration of purple and blue cells going through receptor binding with endocytosis, endosomal acidification, membrane fusion, and uncoated viral genome