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Functions of the dendritic-cell-bound IgE pool in allergy Recent studies of the laboratory on IgE-mediated Th2 responses in food allergy and asthma models showed that allergic responses were significantly less severe in FcεRI-humanized strains than in …
Principal Investigator Olaf A. Bodamer, MD, PhD, FACMG, FAAP Dr. Bodamer obtained his M.D. degree from the University of Heidelberg, Germany and his Ph.D. degree from the University of Saarland, Germany. Following Pediatric residencies in Germany and at …
We have generated a novel database of mutations that affect brain and/or blood serotonin output in rodents. This was possible through searches of the PubMed, Jackson Laboratory, and OMIM databases. In each case, serotonin was characterized slightly …
Google Scholar Page Harvard Catalyst Page cowan-laboratory-publications Cowan Lab | Recent Publications … Cowan Laboratory Publications …
Allergic Diseases Galand, C., Leyva-Castillo, J.M., Yoon, J., Han, A., Lee, M.S., McKenzie, A., Stassen, M., Oyoshi, M.K. and Geha, R.S. IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells. J. All.Clin. Immunol. In …
Judah Folkman (1933-2008) pioneered the field of angiogenesis and its role in pathology, such as in cancer. Angiogenesis is a complex process of many steps. The zebrafish is a good model for analyzing the molecular basis of vasculogenesis and …
A major goal in angiogenesis research has been to inhibit tumor angiogenesis and growth. One approach has been to block NRP expression. Both mouse knockouts and zebrafish knockdowns show that angiogenesis is NRP-dependent. NRP knockdown in zebrafish …
Our research goals The common fundamental goals of the projects are to characterize and understand normal and abnormal patterns of gene expression in developing muscle from the stem cell state through to maturity. Further, we aim to understand the …
More information about all clinical trials can be found at: clinicaltrials.gov More information about Interstitial Cystitis can be found at: Interstitial Cystitis Network More information about Neuromuscular Disorders can be found at: Muscular Dystrophy …
1) Obtain written informed consent 2) Locate specimens To participate we will need: Blood samples from the affected participants and all available and consenting first-degree relatives. Unfixed, frozen muscle tissue, for the Neuromuscular Disorder …