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The Effect of Age on Ligament Healing Once we discovered that this “bioenhanced repair” technique resulted in a repair with equal strength to an ACL reconstruction in young animals, we also evaluated the effect of age on functional ligament healing and …
In-vivo Validation Studies In vivo animal models of ACL injury were then required to translate what we learned in the petri dish to a living organism. ACL transection models (i.e., the Pond-Nuki model) have been historically used to promote joint failure …
Neuroscience Dynamic characterization of brain network maturation in the developing human brain Novel electrophysiological markers of seizure dynamics in the epileptic brain Improved source localization in the anisotropic brain Optimization of imaging …
Physical activity and the developing brain: National Science Foundation Research News (2021) Positive effects of physical activity on the adolescent brain, press release (2021) We congratulate Skylar Brooks for her recent 'On the Spot" award from the …
Brief Description In this study, we are collaborating with Margaret Sheridan (Boston Children’s Hospital and Harvard Medical School) to investigate the role that stress plays in the lives of teenagers. In particular, we are interested in how individual …
Dr. Leonard Zon, along with postdoctoral fellow Dr. Elizabeth Patton and colleagues, genetically engineered this zebrafish to make the mutated form of human BRAF, which caused the fish to develop black-pigmented moles on its skin. When the fish were …
Gene regulation in normal hematopoiesis The hematopoietic system serves a valuable model to study basic gene regulatory mechanisms involved in cell fate decisions and cell maturation. An adult human produces nearly a trillion new blood cells every day. …
Epilepsy We work extensively with the BCH Epilepsy Center on multiple projects. All of our work with the Epilepsy Center has a clear clinical focus, mostly around discovery of biomarkers for epilepsy, comorbid neurological or cognitive effects, and …
Peter A. Nigrovic, M.D. Chief, Division of Immunology, Boston Children’s Hospital Karp Family Research Building One Blackfan Circle 10th floor, RB10211 Boston, MA 02115 clinical office: 617-355-6117 (Boston Children’s Hospital) clinical office: …
Equipment The Proteomics Center at the Boston Children's Hospital is equipped with state of the art instrumentation, which allows our researchers to push the limits with biological mass spectrometry experiments. These resources provide a unique …