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Periodic Fever | Overview


Consensus Treatment Plans for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis Syndrome (PFAPA): A Framework to Evaluate Treatment Responses From the Childhood Arthritis and Rheumatology Research Alliance (CARRA) PFAPA Work Group

Authors: Amarilyo G, Rothman D, Manthiram K, Edwards KM, Li SC, Marshall GS, Yildirim-Toruner C, Haines K, Ferguson PJ, Lionetti G, Cherian J, Zhao Y, DeLaMora P, Syverson G, Nativ S, Twilt M, Michelow IC, Stepanovskiy Y, Thatayatikom A, Harel L, Akoghlanian S, Tucker L, Marques MC, Srinivasalu H, Propst EJ, Licameli GR, Dedeoglu F, Lapidus S; CARRA PFAPA Consensus Treatment Plan Workgroup

Summary: The purpose of this project was to develop consensus treatment plans (CTPs) and response criteria for PFAPA for future studies to generate evidence-based therapeutic guidelines. Dr. Dedeoglu co-lead this project within the Childhood Arthritis and Rheumatology Research Alliance (CARRA).

Publication Information: Pediatric Rheumatology online journal, April 2020

Classification Criteria for Autoinflammatory Recurrent Fevers

Authors: Gattorno M, Hofer M, Federici S, Vanoni F, Bovis F, Aksentijevich I, Anton J, Arostegui JI, Barron K, Ben-Cherit E, Brogan PA, Cantarini L, Ceccherini I, De Benedetti F, Dedeoglu F, Demirkaya E, Frenkel J, Goldbach-Mansky R, Gul A, Hentgen V, Hoffman H, Kallinich T, Kone-Paut I, Kuemmerle-Deschner J, Lachmann HJ, Laxer RM, Livneh A, Obici L, Ozen S, Rowczenio D, Russo R, Shinar Y, Simon A, Toplak N, Touitou I, Uziel Y, van Gijn M, Foell D, Garassino C, Kastner D, Martini A, Sormani MP, Ruperto N; Eurofever Registry and the Paediatric Rheumatology International Trials Organisation (PRINTO)

Summary: Through an international collaborative effort in which Dr. Dedeoglu participated actively, a novel set of classification criteria for hereditary periodic fever syndromes and PFAPA were proposed.

Publication Information: Annals of the Rheumatic Diseases, August 2019

Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Anti-inflammatory Drugs and/or With Active Spinal Lesions

Authors: Zhao Y, Wu EY, Oliver MS, Cooper AM, Basiaga ML, Vora SS, Lee TC, Fox E, Amarilyo G, Stern SM, Dvergsten JA, Haines KA, Rouster-Stevens KA, Onel KB, Cherian J, Hausmann JS, Miettunen P, Cellucci T, Nuruzzaman F, Taneja A, Barron KS, Hollander MC, Lapidus SK, Li SC, Ozen S, Girschick H, Laxer RM, Dedeoglu F, Hedrich CM, Ferguson PJ

Summary: The aim of this study, conducted under the co-leadership of Dr. Dedeoglu, was to develop standardized treatment regimens for chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), so that meaningful data can be generated for use in future studies looking at treatment effectiveness.

Publication Information: Arthritis Care & Research, August 2018

Periodic Fever, Aphthosis, Pharyngitis, and Adenitis Syndrome: Analysis of Patients from Two Geographic Areas

Authors: Batu ED, Kara Eroglu F, Tsoukas P, Hausmann JS, Bilginer Y, Kenna MA, Licameli GR, Fuhlbrigge RC, Özen S, Dedeoglu F.

Summary: Drs. Dedeoglu and Hausmann established a collaboration with several pediatric rheumatologists in Turkey to study children with Periodic Fever, Aphthosis, Pharyngitis, and Adenitis Syndrome (PFAPA Syndrome) in different geographic locations. They demonstrated that PFAPA patients have different symptoms in Turkey when compared to patients in the United States.

Publication Information: Arthritis Care and Research, December 2016