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Shaping the future of pediatric medicine

For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2022, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.

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Institutional Centers for Clinical & Translational Research

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.

Learn More about our resources for the research community

Children with psychotic symptoms may merit genetic testing, finds study

Psychosis in children is extremely rare, but it’s possible, even at as young as age 4. New research finds that some children with psychotic symptoms have DNA duplications or deletions. Joseph Gonzalez-Heydrich, MD and David Glahn, PhD explain how to recognize psychosis in children and the benefits of genetic testing.

Learn more about how genetic testing may help children with psychosis

Chromosomal testing expands options for exploring causes of SIDS

Chromosomal microarray testing is already used routinely to explore the cause of undiagnosed diseases. A new study from the Roberts Program suggest it can help find the cause of SIDS and sudden unexplained child death.

Learn more about sids chromosomal testing

Genetic sequencing may open doors for newborns with hypotonia

When a baby is born with low muscle tone, their future is hard to predict. How should they be cared for? Recent work from the Neonatal Genomics Program argues for first-line comprehensive DNA sequencing to get to a diagnosis and a treatment plan faster.

Learn more about genetic sequencing for newborns