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Shaping the future of pediatric medicine

For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2021, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.

Find a clinical trial

Institutional Centers for Clinical & Translational Research

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.

Learn More about our resources for the research community

Beyond fluid buildup: Rethinking congenital hydrocephalus

Hydrocephalus is largely thought to be caused by a buildup of fluid in the brain. New work turns that view on its head, finding that some children have mutations that disrupt brain development.

Learn more about research on congenital hydrocephalus.

Targeting treatments for vascular anomalies, courtesy of cancer genetics

Vascular anomalies aren’t cancers, but they often involve mutations in the same genes and pathways. Through genetics, Dr. Whitney Eng is matching patients with targeted cancer drugs, improving their quality of life.

Learn more about treatments for vascular anomalies genetics

Clinical trials in children: Is there racial equity?

This review of 10 years of pediatric trials found racial disparities, but not necessarily those one might expect. Explicit efforts should be made to enroll children from different ethnic groups, says Dr. Eric Fleegler.

Learn more about racial equity in clinical trials